Ets2 and Mesp1 generate cardiac progenitors from fibroblasts

A method for modulating cell differentiation capabilities using heterologous gene expression. Some embodiments of the invention relate to a method for inducing a cardiac progenitor cell by delivering a reprogramming factor to the cell, wherein the reprogramming factor comprises ETS2 or a combination of ETS2 and Mesp1.

App TypeCase No.CountryPatent/Publication No.
InquireNational Phase2011011United States9,109,232
InquireNational Phase2011011Canada2791901
InquireNational Phase2011011Europe2542669
InquireNational Phase2011011China102844428