An innovative method for creating an optical fiber capable of light emissions at multiple radial sites along the fiber. Traditional optical fibers only have light delivery at the end of the fiber, which is not ideal for applications, such as neural probes, where light is needed at multiple sites. This unique method utilizes laser micro-machining to create small windows on the sides of the fiber that emit light. Using this method, optical fibers can be specially designed with light emissions at desired locations along the fiber, power outputs required for the application, and preferred output angles. The Houston Methodist Research Institute is currently conducting research and testing this technology as a neural probe in animal models for regenerative medicine applications.