Our technology consists of a non-invasive imaging system that provides real-time, dynamic, quantifiable and clinically-relevant information about blood perfusion within the skin graft during and after transplantation. The proposed methodology is based on an optical technique called Near-InfraRed Spectroscopy (NIRS) which exploits the semi-transparency of human tissues to near-infrared light (650-1000 nm) to investigate properties up to several centimeters in depth. (More in Invention Disclosure Form)