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College of Pharmacy

College of Pharmacy

Faculty Profile

begum-khurshida.jpgKhurshida Begum

Research Scientist
Department of Pharmacy Practice and Translational Research

Office: 
University of Houston College of Pharmacy
Health 2, Room 4044
4349 Martin Luther King Boulevard
Houston, TX 77204-5039

Contact: kbegum@central.uh.edu

Research:

  • Molecular characterization and epidemiology of pathogens
  • C. difficile infection, biofilm formation and pathobiology
  • Infection model and antimicrobial drug resistance
  • WGS and metagenomics
  • Ph.D., Biopharmaceutical Sciences, Okayama University, Okayama, Japan
  • M.S. Zoology, Dhaka University, Dhaka, Bangladesh
  • B.S., Zoology, Dhaka University, Dhaka, Bangladesh

Publications List
  • Mason CS, Avis T, Hu C, Nagalingam N, Mudaliar M, Coward C, Begum K, Gajewski K, Alam MJ, Bassères E, Moss S, Reich S, Duperchy E, Fox KR, Garey KW, Powell DJ. Antimicrob Agents Chemother. 2023 May 17;67(5):e0156322. doi: 10.1128/aac.01563-22. Epub 2023 Apr 24. PMID: 37093023
  • Garey KW, McPherson J, Dinh AQ, Hu C, Jo J, Wang W, Lancaster CK, Gonzales-Luna AJ, Loveall C, Begum K, Jahangir Alam M, Silverman MH, Hanson BM. Efficacy, Safety, Pharmacokinetics, and Microbiome Changes of Ibezapolstat in Adults with Clostridioides difficile Infection: A Phase 2a Multicenter Clinical Trial. Clin Infect Dis. 2022 Sep 30;75(7):1164-1170. doi: 10.1093/cid/ciac096. PubMed PMID: 35134880; PubMed Central PMCID: PMC9525077.
  • Bassères E, Endres BT, Montes-Bravo N, Pérez-Soto N, Rashid T, Lancaster C, Begum K, Alam MJ, Paredes-Sabja D, Garey KW. Visualization of fidaxomicin association with the exosporium layer of Clostridioides difficile spores. Anaerobe. 2021 Jun;69:102352. doi: 10.1016/j.anaerobe.2021.102352. Epub 2021 Feb 25. PubMed PMID: 33640461
  • Begum K, Bassères E, Miranda J, Lancaster C, Gonzales-Luna AJ, Carlson TJ, Rashid T, Eyre DW, Wilcox MH, Alam MJ, Garey KW. In Vitro Activity of Omadacycline, a New Tetracycline Analog, and Comparators against Clostridioides difficile. Antimicrob Agents Chemother. 2020 Jul 22;64(8). doi: 10.1128/AAC.00522-20. Print 2020 Jul 22. PubMed PMID: 32513796; PubMed Central PMCID: PMC7526832
  • Endres BT, Begum K, Sun H, Walk ST, Memariani A, Lancaster C, Gonzales-Luna AJ, Dotson KM, Bassères E, Offiong C, Tupy S, Kuper K, Septimus E, Arafat R, Alam MJ, Zhao Z, Hurdle JG, Savidge TC, Garey KW. 2019. Epidemic Clostridioides difficile Ribotype 027 Lineages: Comparisons of Texas Versus Worldwide Strains. Open Forum Infect Dis. 2019 Feb 9;6(2):ofz013. doi: 10.1093/ofid/ofz013. eCollection 2019 Feb. MID: 30793006
  • Han SJ, Begum K, Foulds CE, Hamilton RA, Bailey S, Malovannaya A, Chan D, Qin J, O'Malley BW. The Dual Estrogen Receptor α Inhibitory Effects of the Tissue-Selective Estrogen Complex for Endometrial and Breast Safety. 2016. Mol Pharmacol. 2016 Jan;89(1):14-26. doi: 10.1124/mol.115.100925. Epub 2015 Oct 20. PMID:26487511
  • Han SJ, Hawkins SM, Begum K, Jung SY, Kovanci E, Qin J Lydon JP, DeMayo FJ, O’Malley BW (2012). A novel isoform of steroid receptor coactivator-1 is critical for pathogenic progression of endometriosis. Nature Medicine 18(7): 1102-1111
  • Begum K, Li B , Beeman RW and Y Park (2009). Functions of Ion Transport Peptide and Ion Transport Peptide-like in the red flour beetle Tribolium castaneum, Insect Biochemistry and Molecular Biology, 39, 717-725
  • Mutti NS, Louis J, Pappan LK, Pappan K, Begum K, Chen MS,Park Y, Dittmer N, Marshall J, Reese JC, and GR Reeck (2008). A protein from the salivary glands of the pea aphid, Acyrthosiphon pisum, is essential in feeding on a host plant., Proc Natl Acad Sci U S A ., 105 (29), 9965-9969
  • Begum K, Kim HS, Kumar V, Stojiljkovic I, Wataya Y (Jun 2003). In vitro antimalarial activity of metalloporphyrins against Plasmodium falciparum, Parasitology Research, 90 (3), 221-4
  • Begum K, Kim HS, Okuda Y, Wataya Y, Kimura M, Huruta T (2002). Genomic analysis of mefloquine-resistant Plasmodium falciparum, Nucleic Acids Research. Supplement (2001) (2), 223-4

Awards & Honors

  • 2013-2016: Ruth L. Kirschstein-NRSA Fellowship, Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX
  • 2001-2003: Rotary International Scholarship, Okayama University, Japan (PhD Study)
  • 1990: Eden College Scholarship, University of Dhaka, Bangladesh (MSc Study)